Scientific question

A central goal of this project is to merge the data from the Crop Proteome Engine into ProteomicsDB, to make it available within the consortium and subsequently to the public. However, the functions of a large part of the proteins are not known, which complicates the interpretation of the results (e.g. differentially regulated proteins) in other projects.

Approach

Systematic mapping of proteins in 100 crop plants allows system-wide integration of protein expression with, among others, plant phylogeny, plant physiology, and sequence homology, allowing inferences to be made about the function of unannotated proteins.

Expected results

The developed method will be applied to the entire ProteomicsDB dataset and will thus contribute to the systematic elucidation of the functions of unannotated and predicted proteins/genes.